全文获取类型
收费全文 | 222864篇 |
免费 | 11657篇 |
国内免费 | 872篇 |
专业分类
耳鼻咽喉 | 2933篇 |
儿科学 | 7179篇 |
妇产科学 | 5007篇 |
基础医学 | 31077篇 |
口腔科学 | 7611篇 |
临床医学 | 16592篇 |
内科学 | 52984篇 |
皮肤病学 | 6495篇 |
神经病学 | 19750篇 |
特种医学 | 5278篇 |
外国民族医学 | 3篇 |
外科学 | 24530篇 |
综合类 | 1024篇 |
一般理论 | 81篇 |
预防医学 | 21432篇 |
眼科学 | 4420篇 |
药学 | 15535篇 |
中国医学 | 967篇 |
肿瘤学 | 12495篇 |
出版年
2023年 | 1643篇 |
2022年 | 1244篇 |
2021年 | 5512篇 |
2020年 | 3446篇 |
2019年 | 5761篇 |
2018年 | 8119篇 |
2017年 | 5303篇 |
2016年 | 5522篇 |
2015年 | 6082篇 |
2014年 | 7514篇 |
2013年 | 10577篇 |
2012年 | 17245篇 |
2011年 | 18143篇 |
2010年 | 9529篇 |
2009年 | 7438篇 |
2008年 | 14561篇 |
2007年 | 15094篇 |
2006年 | 13983篇 |
2005年 | 13512篇 |
2004年 | 12096篇 |
2003年 | 11127篇 |
2002年 | 10235篇 |
2001年 | 4325篇 |
2000年 | 4780篇 |
1999年 | 3807篇 |
1998年 | 1106篇 |
1997年 | 818篇 |
1996年 | 721篇 |
1995年 | 687篇 |
1994年 | 608篇 |
1993年 | 519篇 |
1992年 | 1542篇 |
1991年 | 1244篇 |
1990年 | 1123篇 |
1989年 | 942篇 |
1988年 | 809篇 |
1987年 | 764篇 |
1986年 | 774篇 |
1985年 | 638篇 |
1984年 | 520篇 |
1983年 | 424篇 |
1982年 | 292篇 |
1979年 | 405篇 |
1975年 | 314篇 |
1974年 | 372篇 |
1973年 | 383篇 |
1972年 | 322篇 |
1971年 | 338篇 |
1970年 | 316篇 |
1969年 | 313篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
11.
12.
Francisco Javier P rez Lara Maria Belen Jimenez Martinez Francisco Pozo Mu oz res Fontalba Navas Rogelio Garcia Cisneros Maria Jose Garcia Larrosa Ignacio Garcia Delgado Maria del Mar Callejon Gil 《World Journal of Clinical Cases》2021,9(23):6582-6590
The coronavirus disease 2019, which is caused by severe acute respiratory syndrome coronavirus 2, was first identified in December 2019 in Wuhan, China, and has since spread rapidly, evolving into a full-blown pandemic. We would like to report our experience after 1 year of this pandemic in the surgical service of a district hospital in Spain. There have been many changes (including new protocols) that our service and the hospital have undergone, to adapt to the new situation. We believe that this experience can be useful for other professionals who have lived and are living a similar situation. 相似文献
13.
Crozeta Bruno Monguilhott Lopes Fabiane Carneiro Menezes Silva Renato Silva-Sousa Yara Teresinha Correa Moretti Letícia Freiria Sousa-Neto Manoel Damião 《Clinical oral investigations》2021,25(3):891-899
Clinical Oral Investigations - The aim of this study was to evaluate the efficacy of supplementary techniques (ultrasonic tip/XP-endo Finisher R) in removing remaining filling materials... 相似文献
14.
Antonio Montalvo Afonso Fernando Ruiz Juretschke Rosario González Rodrigálvarez Olga Mateo Sierra Begoña Iza Vallejo Roberto García Leal Marc Valera Melé Vicente Casitas Hernando Jose Manuel Hernández Poveda Carlos Fernández Carballal 《Neurocirugía (Asturias, Spain)》2021,32(1):1-9
Background and objectivesThe treatment of deafferentation pain by spinal DREZotomy is a proven therapeutic option in the literature. In recent years, use of DREZotomy has been relegated to second place due to the emergence of neuromodulation therapies. The objectives of this study are to demonstrate that DREZotomy continues to be an effective and safe treatment and to analyse predictive factors for success.Patients and methodsA retrospective study was conducted of all patients treated in our department with spinal DREZotomy from 1998 to 2018. Bulbar DREZotomy procedures were excluded. A visual analogue scale (VAS) and the reduction of routine medication were used as outcome variables. Demographic, clinical and operative variables were analysed as predictive factors for success.ResultsA total of 27 patients (51.9% female) with a mean age of 53.7 years underwent DREZotomy. The main cause of pain was brachial plexus injury (BPI) (55.6%) followed by neoplasms (18.5%). The mean time of pain evolution was 8.4 years with a mean intensity of 8.7 according to the VAS, even though 63% of the patients had previously received neurostimulation therapy. Favourable outcome (≥ 50% pain reduction in the VAS) was observed in 77.8% of patients during the postoperative period and remained in 59.3% of patients after 22 months average follow-up (mean reduction of 4.9 points). This allowed for a reduction in routine analgesic treatment in 70.4% of them. DREZotomy in BPI-related pain presented a significantly higher success rate (93%) than the other pathologies (41.7%) (p = .001). No association was observed between outcome and age, gender, DREZ technique, duration of pain or previous neurostimulation therapies. There were six neurological complications, four post-operative transient neurological deficits and two permanent deficits.ConclusionDorsal root entry zone surgery is effective and safe for treating patients with deafferentation pain, especially after brachial plexus injury. It can be considered an alternative treatment after failed neurostimulation techniques for pain control. However, its indication should be considered as the first therapeutic option after medical therapy failure due to its good long-term results. 相似文献
15.
16.
José-Luis Andréu María Auxiliadora Martín Héctor Corominas José Javier Pérez-Venegas José Andrés Román-Ivorra Fernando Sánchez-Alonso Ángel Gil de Miguel 《Reumatología clinica》2021,17(4):212-214
IntroductionThe current paradigm of the management of rheumatoid arthritis (RA) recommends achieving a state of remission or low disease activity through the treat-to-target strategy. Our study assesses adherence to this strategy.MethodPatients with RA (ACR-EULAR 2010 criteria) were included. From each centre, 19 patients were randomly selected. Clinical histories (CH) were assessed by independent auditors, checking compliance with predefined quality criteria. The study was approved by ethics committees.ResultsWe included 856 patients (mean age 54 years; 71% women). The use of a combined index (CI) was recorded in 61% of cases. Visits were recorded every 4 weeks using a CI in 4% of CH while attempts were made to achieve remission. Monitoring of disease activity every 6–8 months after reaching the target was recorded in 73% of cases.ConclusionsThe implementation of the treat-to-target strategy is barely recorded in patients with RA in routine clinical practice. 相似文献
17.
18.
19.
J. Ripollés-Melchor C. Aldecoa E. Alday-Muñoz S. del Río A. Batalla E. del-Cojo-Peces R. Uña-Orejón J.L. Muñoz-Rodés J.V. Lorente Á.V. Espinosa C. Ferrando-Ortolà J.L. Jover A. Abad-Gurumeta J.M. Ramírez-Rodríguez A. Abad-Motos 《Revista espa?ola de anestesiología y reanimación》2021,68(7):373-383
BackgroundThe optimal regimen for intravenous administration of intraoperative fluids remains unclear. Our goal was to analyze intraoperative crystalloid volume administration practices and their association with postoperative outcomes.MethodsWe extracted clinical data from two multicenter observational studies including adult patients undergoing colorectal surgery and total hip (THA) and knee arthroplasty (TKA). We analyzed the distribution of intraoperative fluid administration. Regression was performed using a general linear model to determine factors predictive of fluid administration. Patient outcomes and intraoperative crystalloid utilization were summarized for each surgical cohort. Regression models were developed to evaluate associations of high or low intraoperative crystalloid with the likelihood of increased postoperative complications, mainly acute kidney injury (AKI) and hospital length of stay (LOS).Results7,580 patients were included. The average adjusted intraoperative crystalloid infusion rate across all surgeries was to 7.9 (SD 4) mL/kg/h. The regression model strongly favored the type of surgery over other patient predictors. We found that high fluid volume was associated with 40% greater odds ratio (OR 1.40; 95% confidence interval1.01-1.95, p = 0.044) of postoperative complications in patients undergoing THA, while we found no associations for the other types of surgeries, AKI and LOSConclusionsA wide variability was observed in intraoperative crystalloid volume administration; however, this did not affect postoperative outcomes. 相似文献
20.